Endoscopic Endonasal Transsphenoidal Approach for Pituitary Adenomas: a Prospective Review of Our Early Experience
نویسندگان
چکیده
Background & Aim: Pituitary adenomas are part of a dissimilar group of benign neoplasms. The development of endoscopic techniques for surgery of paranasal sinuses has increased the opportunity for an endoscopic approach with regard to the pituitary gland. Minimally invasive endoscopic pituitary surgery, in turn, permits a more thorough tumor resection and fewer associated surgical complications. This study aimed to determine the descriptive outcomes and the complication rates for endoscopic transsphenoidal hypophysectomies. Methods & Materials/Patients: A prospective study was conducted from November 2012 to March 2015. 28 patients with proven symptoms of pituitary adenomas were included in this study, and regularly attended follow-up sessions. Results: In our study, we have operated on 28 patients with hypophysis adenoma with the help of an endoscopic setting. The male to female ratio was 1:2.5, with average age range of 35 to 45 years. Growth hormone (GH) adenoma appeared in 36% (10 patients), prolactinoma in 21% (6 patients), Cushing’s disease in 18% (5 patients) and non-functional adenoma in 18% (5 patients). Gonadotroph adenomas were the least common at about 7%. The most common symptoms in our series were headache and visual defects. 5 patients including 2 with prolactinoma and 3 with GH adenoma presented apoplexy signs and symptoms. Conclusion: Our series demonstrated that the endoscopic approach not only allows well anatomical visualization, and therefore facilitates the full oncological resection of tumors, but also reduces the incidence of pre-operative complications.
منابع مشابه
Endoscopic Endonasal Transsphenoidal Approach for Pituitary Adenomas: a Prospective Review of Our Early Experience
Background & Aim: Pituitary adenomas are a part of a dissimilar group of benign neoplasms. The development of endoscopic techniques for surgery of paranasal sinuses has increased the opportunity for an endoscopic approach with regard to the pituitary gland. Minimally invasive endoscopic pituitary surgery, in turn, permits a more thorough tumor resection and fewer associated surgical complicatio...
متن کاملManagement of Pituitary Adenomas: Mononostril Endoscopic Transsphenoidal Surgery
Introduction: The endoscopic transsphenoidal approach for pituitary adenomas and other sellar lesions is quickly becoming the procedure of choice in their surgical management. The most common approach is binostril three-hand technique which requires a large exposure and subjects both nasal cavities to potential trauma. To reduce nasal morbidity, we employ a mononostril two-hand technique with t...
متن کاملA Prospective Study To Evaluate The Role Of Perioperatve Cerebrospinal Fluid Diversion By Lumbar Drain In Transnasal Transsphenoidal Tumor Surgeries
Background &Aim: The endoscopic endonasal transsphenoidal approach has been widely employed as a treatment for pituitary adenomas and other parasellar tumors. However, the major concerns related to endoscopic endonasal transsphenoidal surgery include the risks of CSF leak post-operatively leading to morbidity and at times mortality due to severe meningitis. Several studies in the past have foun...
متن کاملSurgical outcomes of the endoscopic endonasal transsphenoidal approach for large and giant pituitary adenomas: institutional experience with special attention to approach-related complications.
Objective In this study, we investigate our institutional experience of patients who underwent endoscopic endonasal transsphenoidal approach for treatment of large and giant pituitary adenomas emphasizing the surgical results and approach-related complications. Method The authors reviewed 28 consecutive patients who underwent surgery between March, 2010 and March, 2014. Results The mean preoper...
متن کاملMicroscopic Transsphenoidal Surgery for Pituitary Adenomas in Children and Adolescents
Background & Aim: We described the presentation, management and subsequent treatment outcomes of children and adolescents diagnosed with a pituitary adenoma in a joint neuroendocrine setting followed up by a single service as well as assessing long-term outcomes in terms of endocrine status and neurology symptoms. Methods & Materials/Patients: A total of 21 participants with histologically v...
متن کامل